1. 'Lose Yourself'
This 2002 staple was written during filming for the 8 Mile film, and throughout, it channels the intensity of Em's character, "B-Rabbit," preparing for a rap battle. "His palms are sweaty / knees weak, arms are heavy," Mathers rhymes, narrating his own movements to the stage, "There's vomit on his sweater already / mom's spaghetti." In terms of pure lyricism, "Lose Yourself" is one of the rapper's finest achievements, and the rapped-sung hook is far and away the best in his discography. But let's not forget the work of producer/co-writer Jeff Bass, who contributed one of the most instantly recognizable guitar riffs of all-time.