Pharmakon is the New York noise auteur Margaret Chardiet, a true connoisseur of screech. She likes to make her industrial-sounding gadgets scream and howl in agony, an electro-nightmare expression of her inner turmoil. And probably yours, too – if not, she'll make sure you taste the pain before you get a chance to lower the volume. Her second album, Bestial Burden, hits with the full impact of her hyperconfrontational live shows. Chardiet has said that she began composing the songs in bed while recuperating from major surgery, which makes all the sense in the world. With her heavily processed voice floating through the feedback, it's the remarkably detailed cry of a soul on fire.