Readers' Poll: 10 Best Music Videos of 2000s

See which video beat favorites from the White Stripes, OutKast, Britney Spears

10. Britney Spears, "Toxic"

Spears nixed the shock and awe of her Britney era and displayed a more settled, comfortable maturity on In the Zone, with single "Toxic" serving as the premiere example of her transition. The star transforms into a double-agent in the adventurous, sexy and creative clip that has become one of the most easily identifiable images of the pop princess. It's long-lasting legacy is not only a part of pop music as a whole, it has stayed with Spears through all her eras, with the star creating sequels to the clip in the visuals for "Break the Ice" and "Womanizer" later on in her career.