Gorillaz, Madonna and De La Soul, "Feel Good Inc."/"Hung Up" (2006)
Damon Albarn's cartoon band took three-dimensional holographic form for the night, with bassist Murdoc in cape and undies, Russel Hobbs looming enormous over his tiny drum set and singer 2D preening, as frontmen will do. De La Soul leap out energetically onstage, eventually bursting into the hysterical laughter of men who never expected to appear on a major television awards show rapping with a cartoon. (Unimpressed, prima donna 2D looks at his phone while they rap.) Then Noodles strolls casually to perch on a stool and strum an acoustic guitar, soon joined by Madonna, leggy and vibrant, to perform "Hung Up." Eventually, her non-holographic band and backing dancers fill the stage.