The Fate of Seymour
In "Jurassic Bark" (November 17th, 2002), Fry gets his hands on the fossilized remains of his beloved dog, Seymour. Fry hadn't seen his dog since he'd gotten frozen in the cryogenics lab 1,000 years earlier, and Professor Farnsworth figures out a way to clone the dog and bring him back. But Fry ultimately decides against it, assuming that Seymour moved on and lived a happy life after Fry disappeared. Then comes one of the most tear-jerking montages ever put to animation, when it's revealed that Seymour spent the rest of his years waiting patiently outside Panucci's Pizza for his master to return.
"Notice that I'm sadistically chuckling at this thought of the dog dying . . . I apologize. I shouldn't be laughing. I'm sorry about that," Cohen says. "It's not a laugh of humor, but a laugh of triumph. Whenever we're hoping to get fans to tear up and it works, I have this little momentary, sadistic laugh of triumph."