8. Walter White and Jesse Pinkman, 'Breaking Bad'
Among all the pairings on this list, Walter White and Jesse Pinkman embodied the widest variety of archetypes. Student and teacher, master and servant, father and son, hero and villain — over the course of Breaking Bad's five-plus seasons, Bryan Cranston and Aaron Paul were tasked with playing all these relationships and more. Not bad, considering that Jesse wasn't intended to last longer than the first season. Instead, his increasingly warped connection to mild-mannered chemistry teacher turned mass-murdering meth kingpin called "Heisenberg" drove one of the greatest drams of all time, from start to finish.