47. Lenny and Squiggy, 'Laverne and Shirley'
A shout-out, of course, to the titular duo played by a tough-talking Penny Marshall and a perpetually perky Cindy Williams — but Laverne & Shirley is one of many sitcoms in which the obnoxious neighbors stole the show. That would be Leonard Kosnowksi and Andrew Squiggman — known for their diminutive nicknames, trademark "Hello!" entrance, greaser aesthetic, and unrelenting idiocy. (Watching Michael McKean and David Lander inhabit these proto-Dumb & Dumber roles is a particular trip today if you've seen McKean kill it as a dramatic actor in Better Call Saul.)