12. Don Draper and Peggy Olson, 'Mad Men'
At first, Matthew Weiner's instant-classic prestige-drama period piece seemed like the story of the tall, dark, and handsome mystery man whose silhouette appeared in the credits. As time passed, however, both Don Draper and his protégé Peggy Olson emerged as co-protagonists, with his downward spiral and her tortuous upward climb past the glass ceiling given more or less equal time. Their final phone call is the show's most moving moment; when you go back and watch the series' best episode "The Suitcase," you realize there was a great two-hander embedded in Mad Men just dying to get out.