6. Cersei Lannister
The fact that no one ever thinks to call her by her married name, Cersei Baratheon, says a lot about the villainous Queen Regent. For example, it says "She marches to the beat of her own drum." Also? "She fucks her twin brother." As a woman, she battles for a place at the table in a world made for men, by men; as a mother, she'd do anything to protect her inbred brood; as a player of the game, she coined the show's catchphrase: "You win or you die." And she'd rather die than give you control.