Anyone thinking of creating a spinoff should study Frasier. Its creators not only took one of the more intriguing characters from a hit show, they moved him to a different city and gave him a different job and a whole new set of friends. Detailed knowledge of the Cheers universe wasn't necessary to enjoy Frasier, and the show was well-established before any of the old gang stopped by for a visit. It ran for 11 seasons and really didn't begin to run out of gas until the very end. A therapist with a radio call-in show can only have so many adventures, but it was great while it lasted.