10. St. Elsewhere, 'The Last One' (1988)
File under: Huh? In one of the more bizarre endings to a series (especially such a respected one), this quirky medical drama turned out to be an imaginary tale dreamt up by the autistic son of would-be doctor Donald Westphall (Ed Flanders). Apparently, the lad had been staring endlessly into a snow globe that housed a miniature version of the hospital and created an elaborate alternate universe for his family. Yup, bet you didn't see that one coming. It was an oddball but original way to end the NBC show, which ran for six critically acclaimed years from 1982-1988.