32. Constance Langdon, 'American Horror Story'
We'll say this for Ryan Murphy's over-the-top anthology series: When it comes to creating memorable villains for talented actresses, the show is an assembly line. Take Constance Langdon, the murderous woman scorned at the center of the show's first season, commonly called "Murder House." Leaving a trail of dead bodies and cutting one-liners in her cigarette-scented wake, she was played by Jessica Lange like a one-woman crossover between Sunset Boulevard and The Amityville Horror.