27. 'Inside Amy Schumer' (2013- )
If things had worked out differently, Amy Schumer's breakout Comedy Central hit — a lively combination of standup, sketches and interview segments — might have ended up a traditional talk show. Figuring that's what the network wanted, the New York comedienne resigned herself to her fate until an executive producer advised, "I think you should make the show you want to make, the show of your dreams." Good thing she listened: Since its debut in the spring of 2013, Inside Amy Schumer hasn't just been hilarious but also zeitgeist-y wise about dating and friendship in the social-media age. Mocking men's fascination with girls who are just one of the guys, Schumer's a secret subversive wielding a deceptively innocuous gal-next-door smile.