40. Roseanne Rosannadanna
Gilda Radner's immortal frizzy-haired wiseass, snapping her gum and discussing boogers, warts and nose hair, while Jane Curtin squirms in disgust. Roseanne was always a divisive gal — for some fans, she was an early example of an SNL character who got recycled way too many times. But she's gained a whole new resonance in the age of the social-media overshare. We are all Jane Curtin now.
Best line: "It's always something."