When it came time to mount a Friends spin-off, do you think the show's producers opted for Ross and Rachel raising kids in the suburbs of Yonkers, or Phoebe taking over Central Perk's management with hilarious results? No, they went with Joey Tribbiani moving to Los Angeles to become a movie star, throwing in a tough-talking Italian-American sister (et tu, The Sopranos' Drea de Matteo?), a nephew and a horny female agent. The fact that they gave it the same prime Must-See-TV slot that the original sitcom-of-a-generation held on Thursday night must have seemed like a great idea for keeping fans tuned in. But it also invited a lot of very unflattering comparisons to the popular show — and viewers stopped saying "I'll be there for you" to Joey's Hollywood misadventures long before its two seasons were finished. Matt LeBlanc managed to bounce back nicely (if you're not watching his meta-comedy Episodes on Showtime, you should be), but this pretty much put a stake through any future Friends' endeavors.