3. R.E.M. - 'Everybody Hurts'
There weren't a lot of R.E.M. songs with a straightforward message before "Everybody Hurts." "The One I Love" is an anti-love song, "Gardening at Night" is just confusing and we're still trying to figure out "Losing My Religion." But there's no mistaking the message of "Everybody Hurts" – it's right there in the title. The iconic video showing depressed people in a traffic jam was filmed in San Antonio, Texas. MTV played it all the time in 1993, making this one of R.E.M.'s most well-known songs.