1. Eric Clapton - 'Tears in Heaven'
Eric Clapton's son Conor was just four years old when he fell to his death from the 53th floor of a New York building in 1991. Not long after the tragedy, Clapton and songwriter Will Jennings penned "Tears in Heaven" as a tribute to the child. They never imagined it would become a huge hit, but within months, it was Number Two on the Hot 100 and swept the Grammys. The song first appeared on the soundtrack to the widely forgotten Jason Patric movie Rush, but the version most people remember comes from Clapton's 1992 Unplugged special. By 2004, Clapton could no longer bear to perform the song at his shows and he dropped it; it returned earlier this year.