10. 'The Perfect Drug' (TIE)
Tasked with writing a track for David Lynch's 1997 film Lost Highway, Reznor entered the studio and, after a week or so of experimentation, emerged with the manic head trip that is "The Perfect Drug." Despite being a well-received single stuffed with Reznor's reflections on imperceptibility ("I come along/ But I don't know where you're taking me"), Nine Inch Nails have never performed the song live. Perhaps this is due to Reznor's admittedly underwhelming feelings about the cut. "I'm not cringing about it, but it's not my favorite piece," he said in 2005. "If they said play me, y'know, the top hundred songs you've written, that probably wouldn't be in the top hundred."