James Hetfield, Sammy Hagar Headline San Francisco's Acoustic-4-A-Cure Event

Jerry Cantrell, Pat Monahan, Chad Smith, Joe Satriani and Linda Perry also booked for the benefit concert

Sammy Hagar and James Hetfield return for their annual Acoustic-4-A-Cure charity concert. Credit: Denise Truscello/Getty

Sammy Hagar and Metallica's James Hetfield will headline their second annual Acoustic-4-A-Cure event at San Francisco's the Masonic on May 15th. Alice in Chains' Jerry Cantrell, Train's Pat Monahan, Linda Perry and Hagar's fellow Chickenfoot members guitarist Joe Satriani and Red Hot Chili Peppers drummer Chad Smith will join the Bay Area-based music legends. All proceeds from the event will be used to fund children's brain tumor research at UCSF Benioff Children's Hospital.

Tickets for Acoustic-4-A-Cure, which promises "once-in-a-lifetime musical moments, duets, jams and surprise guests planned," will go on sale April 10th at 10 a.m. PST at Live Nation. The event was co-created by Hagar and Hetfield, both Bay Area residents, to raise needed funds and awareness for the Pediatric Cancer Program at UCSF Benioff Children's Hospital. Check out the concert's official site for more details.

The inaugural 2014 Acoustic-4-A-Cure featured Hetfield and Hagar alongside returning guests Satriani and Monahan plus Green Day's Billie Joe Armstrong and Heart's Nancy Wilson. Hetfield performed the Beatles' "In My Life" on acoustic guitar, while Hetfield, Armstrong and Satriani teamed up for a rendition of Bob Seger's "Turn the Page," a track Metallica has often covered in concert. The concert also included Green Day performing "Boulevard of Broken Dreams" and an all-star version of Bob Dylan's "Rainy Day Woman #12 & 35."

This year's Acoustic-4-A-Cure concert comes just four days before Hagar releases his new live album At Your Service, featuring Van Halen classics, Hagar's solo hits, Chickenfoot tracks and covers from artists like Led Zeppelin and Montrose.