Guns N' Roses
When you put a bunch of junkies and a megalomaniac in a band together, the shit will hit the fan sooner or later. In the case of Guns N' Roses, that moment came pretty quickly. The group hit it big with the release of Appetite for Destruction in 1987, but just three years later they pushed out original drummer Steven Adler due to his severe drug addiction. GNR carried on, but Axl Rose started showing up for shows ridiculously late. According to Slash and Duff McKagan, he refused to go onstage one night until they signed away the rights to the band's name. (Axl refutes this.)
Whatever happened, when the Use Your Illusion tour ended in late 1993, the group members went their own separate ways. Since then, things have only gotten worse between the original crew. Axl called Slash a "cancer" and refused to even attend the Rock and Roll Hall of Fame induction because his ex-bandmates would be in the room. As Taylor Swift would say, they are never, ever, ever getting back together.