1. Beta, Denver
Everything about this place is huge, from the headlining DJs (Skrillex, Deadmau5, John Digweed) to the liquid-nitrogen-fueled fog machine (they go through 1,000 liters a night) to the monster 72,000-watt sound system – which you can hear booming from blocks away. "We get so much shit from our neighbors because it's so loud," says one of the club's execs. "The bass just bounces off the concrete." Opened five years ago by Brad Roulier, who co-founded EDM download giant Beatport, Beta has become a major mecca for serious dance music heads and casual partiers alike. "People who have never partied in Denver don't really understand how hard they go here," says rapper Talib Kweli.
Fun Fact: Beta is an easy drive from Red Rocks Amphitheatre, which our panel voted the coolest amphitheater in the country. For a truly memorable weekend, rock out at Red Rocks, then head here for the afterparty of a lifetime.