1. Gnarls Barkley, 'Crazy'
In this frazzled and fragmented decade, when the Top 40 broke down into squabbling niches, the idea of a universal pop hit, a song anybody could love, seemed like a sweet old-fashioned notion. Then these guys showed up. Atlanta rapper Cee-Lo and indie producer Danger Mouse decided it would be a gas to pretend to be the world's greatest pop group, and so they gave the world "Crazy." Everybody loved this song, from your mom to your ex-girlfriend's art professor. It blasted in punk clubs and Burger King bathrooms. Every sucky band on earth tried a lame cover. For the summer of 2006, "Crazy" united us all into one nation under a groove. Gnarls Barkley packed a career's worth of genius ideas into three minutes — and then they basically disappeared. Does that make them crazy? Probably. But was this the most glorious pop thrill of our time? Totally.