100 Best Songs of the 2000s

Eminem, 'Lose Yourself'
12/100

12. Eminem, 'Lose Yourself'

A megahit from the 8 Mile soundtrack, "Lose Yourself" was hip-hop as inspirational as Rocky, with Em rapping about the kind of poverty he grew up in — and showing the superhuman rhyme powers that got him out of it.

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