Season One, Episode Two: Sookie Stackhouse Drinks Bill Compton's Blood for the First Time
The unbreakable bond between Bill and Sookie is formed at the beginning of the second episode, when Sookie, having been beaten within an inch of her life, drink's Bill's blood in order to survive. In the previous episode, Sookie had saved Bill from the Rattrays, a husband-and-wife team who wanted to sell his blood on the black market (in the True Blood world, vampire blood, a.k.a. "V," is the drug du jour), and now the Rattrays have beaten Sookie as payback for their lost revenue. Bill's blood not only heals Sookie within seconds, but works as a homing device. He can always sense her presence, and more important, if she is in trouble. The blood exchange also gave birth to one of TB's most campy, oft-used lines: "Sookie is mine."