20. 'Hedwig and the Angry Inch'
Hedwig and the Angry Inch started as musical in 1998 and has had a longer lifespan than most anyone could have imagined. The original off-broadway play quickly developed a huge following and within three years it was on the big screen, John Cameron Mitchell directing and playing the role of the East German transgender punk singer. The film didn't make much money, but it slowly earned back its budget due to DVD sales. It's back on Broadway now with Neil Patrick Harris. Fans of How I Met Your Mother had no idea what they're in for.