38. Patton Oswalt
Oswalt helped bring stand-up to indie-rock clubs with the Comedians of Comedy tour, and he's spent years skewering American excess and stupidity. After starring on The King of Queens and in films like Young Adult and Ratatouille, he wrote Zombie Spaceship Wasteland, a book of essays about growing up as a geeky outsider. He's also willing to suffer for a joke: Upon admitting he¹d never actually eaten KFC's Famous Bowl, a dish he called a "failure pile in a sadness bowl" in one of his most beloved bits, he agreed to try one and wrote about his near-death meal experience for the AV Club.