19. David Cross
Cross has been busy in recent years: He created and starred in his own IFC series, The movies, and is currently reprising his most famous role, as "analrapist" Dr. Tobias Funke on Arrested Development. And he continues to kill as a stand-up, releasing three comedy albums in the last decade. The most recent, 2010's Bigger and Blackerer, reminds you that he's got supreme skills as a political comedian and a Carlin-esque gift for skewering American absurdity, with excellent bits about Mormons, gimmicky Coors Light cans, and the root of his lifelong depression: "Very recently I discovered that, the entire time, I had a rock in my shoe."