43. 'Usagi Yojimbo,' Stan Sakai
Basically spinning out of the idea that rabbit ears look cool tied in a samurai topknot, Sakai based his rabbit ronin on the legendary swordsman Miyamoto Musashi, mixed with plenty of Kurosawa and cheaper samurai fare. Thirty years later, Sakai is up to volume 27 (!) of Usagi's collected adventures, making for one of the longest running independent comics around. Never less than thoughtful and entertaining, Usagi Yojimbo is one of the most consistent comics around. That's no small feat, but Sakai is a total pro and a consummate craftsman.