38. 'Saga,' Brian K. Vaughan and Fiona Staples
Best known as the author of the Vertigo series Y the Last Man, Vaughan decamped for Hollywood for a spell, working on Lost and Under the Dome. Then he made a monumental return to comics with this
science-fantasy story that's as much about unconventional parents as it is a space opera about warring races, magic and closeted gay robots. Vaughan swears it will always stay a comic; may it run for 1,000 issues.